Celgene discovery and development focus areas include:
Protein Homeostasis
Maintenance of protein homeostasis is a critical function of the cell, and disruptions of this process contribute to the development of numerous diseases, including cancer.
Celgene is developing cancer treatments directed at key biological pathways in protein homeostasis.
Immuno-oncology
Celgene is exploring immuno-oncology therapies targeting multiple cell types associated with anti-tumor responses.
We are actively researching the modulation of the immune system to attack cancer cells.
Inflammation & Immunology
Celgene is focused on applying a deep understanding of human biology to therapeutically modulate the immune system in defined patient subsets, with the ultimate goal of curing patients suffering from devastating illnesses.
Epigenetics
The genome provides instructions for synthesis of proteins and non-coding RNAs.
Celgene is developing a diverse array of therapeutics to target all major components of the cancer epigenome.
Neuroscience & Imaging
Celgene is focused on novel approaches to the prevention of neurodegeneration and neuroinflammation caused by abnormal protein production and processing within the central nervous system, together with imaging techniques that enable early assessment of the therapeutic potential of drug candidates.